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All Journal Jurnal Kedokteran Diponegoro Biota: Jurnal Ilmiah Ilmu-Ilmu Hayati Journal of Biomedicine and Translational Research The Indonesian Biomedical Journal Media Medika Muda Medica Hospitalia Journal of Public Health Research and Community Health Development (JPH RECODE)
Indranila Kustarini Samsuria
Department Of Clinical Pathology, Faculty Of Medicine, Diponegoro University
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Dentistry Health Professions Medicine & Pharmacology Nursing Public Health

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Journal : Jurnal Kedokteran Diponegoro

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Vitamin D Deficiency Linked To Depression (Systematic Review: Meta Synthesis) Talitha Salsabila; Indranila Kustarini Samsuria; Dwi Retnoningrum; Indah Saraswati
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 10, No 5 (2021): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v10i5.30058

Abstract

Background: Depression is a mood disorder that is marked by a persistent feeling of sadness, loss of interest; reduced energy and vitality; feelings of low self-worth or guilt; loss of appetite; disturbed sleep or insomnia; and slowness of thought or action. Vitamin D deficiency has been associated with depression. When the level of Vitamin D and serotonin is low, that leads to depression.Objective: To analyze whether vitamin D deficiency or insufficiency is associated with depression.Method: This is a Systematic Review Report. Samples were gathered from two journals – PubMed and Science Direct with specific search terms used were 'vitamin D' and 'depression', then were adjusted based on the inclusion criteria and research question. After that, the findings are combined in order to reach a conclusion so that the research question is well answered.Results: There are eleven journals that describe a link between low level of Vitamin D and symptoms of depression. The connection between the two is formed due to the neuroprotector and immunomodulatory effects of Vitamin D.Conclusion: Previous studies have shown that Vitamin D deficiency linked to depression. Keywords : Depression, level of vitamin D, vitamin D serum.
THE DIFFERENCE OF MEAN PLATELET VOLUME AND PLATELET COUNT IN CORONARY HEART DISEASE PATIENTS WITH ACUTE CORONARY SYNDROME AND NON ACUTE CORONARY SYNDROME Aditya Paelo Rizki Sikumbang; Indranila Kustarini Samsuria; Novi Anggriyani; Charles Limantoro
JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL) Vol 10, No 2 (2021): JURNAL KEDOKTERAN DIPONEGORO (DIPONEGORO MEDICAL JOURNAL)
Publisher : Faculty of Medicine, Universitas Diponegoro, Semarang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dmj.v10i2.29460

Abstract

Background: Coronary Heart Disease (CHD) is currently one of main causes and the first death in developed and developing countries, including Indonesia. CHD appeared with the clinical appearance of asymptomatic, stable angina pectoris until acute coronary syndrome. ACS is a progressively CHD and takes parameters that describe the process pathogenesis. MPV and platelet count are two parameters in the complete blood count which reflect the activity of platelets in CHD.Objective: This study is to investigate the differences Mean Platelet Volume and Platelet Count in CHD with ACS compared to non ACS.Methods: A cross-sectional study was conducted with collecting data from the medical records of patients with CHD who underwent treatment in the dr. Kariadi General Hospital Medical Center Semarang, the period of January - December 2019. Eighty subjects of 20 non-ACS patients and 60 ACS patients were included in this study which is Mean Platelet Volume and Platelet Count in hematology laboratory were analyzed. The Independent T-test were used for comparing the group means.Results: MPV was found to be higher significantly among ACS patients as compared to non ACS, 9,43 ± 0,3868 fl vs 9,43 ± 0,3868 fl (p-value<0.01) while Platelet Count was lower significantly among ACS patients as compared to non ACS, 282,63 ± 75,084 109/L  vs 322,30 ± 41,980 109/L.Conclusion: There were significantly differences in Mean Platelet Volume and Platelet count between patients with ACS and non ACS.
Co-Authors Ade Delpita Aditya Paelo Rizki Sikumbang Ajeng Kurnia Wardhani Asri Ragil Kemuning Banundari Rachmawati Bilma Riasari Guspa Charles Limantoro Diah Ayu Kusuma Dolly Dolly Dwi Retnoningrum Edward Kurnia Setiawan Limijadi Hadian Widyatmojo Herniah Asti Wulanjani Herniah Asti Wulanjani Indah Saraswati Mabruratussania Maherdika Meita Hendrianingtyas Muji Rahayu Muji Rahayu Novi Anggriyani Nyoman Suci Widyastiti Peni Kistijani Samsuria Ria Triwardhani Ria Triwardhani Talitha Salsabila